Peptide Storage Guidelines

Proper storage of peptides is essential to maintain their stability, integrity, and bioactivity for your research applications. This guide provides general recommendations for storing CHPeptides products.

IMPORTANT DISCLAIMER: The storage guidelines provided below represent general practices in the research field and are provided for informational purposes only. CHPeptides does not guarantee any specific results and is not responsible for any damages, losses, or injuries that may result from following these guidelines. Each research environment is unique, and researchers should use their professional judgment when handling and storing peptides. These guidelines do not constitute professional advice for specific research applications.

General Storage Principles

The stability of peptides is influenced by several factors:

• Temperature
• Moisture exposure
• Light exposure
• pH conditions
• Oxygen exposure
• Physical handling

Storage Recommendations by Form

Lyophilized Peptides

For maximum shelf life and stability:

• Primary Storage: -20°C freezer
• Long-term Storage: -80°C freezer
• Container: Original sealed vial with desiccant
• Protection: Protect from moisture (use desiccator if available)
• Expected Stability: 1-2 years when stored properly

Reconstituted Peptide Solutions

After reconstitution:

• Short-term Storage (up to 1 week): 2-8°C
• Medium-term Storage (up to 3 months): -20°C
• Long-term Storage: -80°C
• Container: Polypropylene tubes in small aliquots
• Avoid: Repeated freeze-thaw cycles
• Recommendation: Prepare small aliquots for single use

Liquid Formulations

For pre-dissolved peptides:

• Storage Temperature: As specified on product documentation (typically -20°C)
• Aliquoting: Divide into single-use portions before freezing
• Protection: Keep tightly sealed to prevent evaporation
• Expected Stability: As indicated on the product specification sheet

Factors Affecting Peptide Stability

Temperature

• Higher temperatures accelerate degradation
• Freezing preserves peptide integrity
• Avoid rapid temperature changes

Moisture

• Moisture can promote hydrolysis of peptide bonds
• Keep lyophilized peptides in sealed containers with desiccant
• Allow refrigerated or frozen peptides to reach room temperature before opening to prevent condensation

Light Exposure

• Some peptides are photosensitive
• Store in amber vials or wrap containers in aluminum foil
• Minimize exposure to direct light, especially for peptides containing tryptophan, tyrosine, or cysteine

pH Conditions

• Most peptides are stable at mildly acidic pH (4-6)
• Avoid strongly acidic or basic conditions unless specifically required
• Buffer selection is critical for reconstituted peptides

Reconstitution Recommendations

When preparing peptides for use:

1. Allow the peptide vial to reach room temperature before opening
2. Choose an appropriate solvent based on peptide properties:
   • Water for hydrophilic peptides
   • Dilute acetic acid (0.1%) for basic peptides
   • DMSO or acetonitrile/water mixtures for hydrophobic peptides
3. Add solvent slowly, allowing the peptide to dissolve gradually
4. Avoid vigorous vortexing which can cause foaming and aggregation
5. For difficult-to-dissolve peptides, gentle sonication may help

Quality Monitoring

To ensure continued peptide quality:

• Note any changes in appearance
• Document reconstitution date and conditions
• Test bioactivity before critical experiments
• Follow expiration dates provided on product documentation

REMINDER: These storage guidelines are provided for general research purposes only. CHPeptides makes no representations or warranties regarding the suitability of these guidelines for your specific research applications. Always use proper laboratory safety procedures when handling research materials.